DNA microarray.
<P>
<BR><LI> Isolate mRNA from a tissue sample.
<BR><LI> Make cDNA by reverse-transcription, using fluorescent nucleotides.
<BR><LI> Each  spot  of  the microarray contains DNA of known sequence from
known alleles.
<BR><LI> Let  the  cDNA  hybridize (base-pair with complementary sequences)
with DNA on the microarray
<P>
   The fluorescence patterns of hybridized DNA reveals gene expression of
   the tissue.
<P>
   Testing for alleles:  <A ClAsS=MID Href="../../../med/Vid/Discover2e/ch18a02_SNP-polymorphysim_microarray-chip.swf" oNClick="popurlt('../../../../med/Vid/Discover2e/ch18a02_SNP-polymorphysim_microarray-chip.swf');txtcolor('microarray1','gray');return false;" Id=microarray1><iMg sRc="/images/shockwave.gif" aLt='' boRDer=0></A>